Anticoagulant Medications
Do not use if taking prescription anticoagulants without consulting a healthcare professional first.
Study Reports
Independent Testing.
Openly Shared.
Three supplied reports from two laboratories, with the findings and source limitations explained below.
Study 01
Repeated Insult Patch Test
Eurofins | CRL, Inc. · Piscataway, NJ
The supplied Repeated Insult Patch Test report states that 240 male and female subjects aged 18–70 were selected and 221 completed the study, including 109 with self-perceived sensitive skin. No adverse events were reported during the RIPT.
Study record
- Study Number
- ECRLNJ2025-0577
- Study Population
- 221 completed (240 selected; ages 18–70)
- Self-Perceived Sensitive Skin
- 109 of 221 completers
- Fitzpatrick Phototypes
- I through VI represented
- Principal Investigator
- Winston Moy, MD
- Study Conduct
- Report states applicable ICH GCP standards were followed
- RIPT Adverse Events
- ✓ None reported during the study
- Study Period
- June 13 – August 8, 2025
0
RIPT Adverse Events
221 subjects completed the RIPT, including 109 with self-perceived sensitive skin. No adverse events were reported during the study.
"The test material identified as Hirudin Topical Serum did not demonstrate a potential for eliciting dermal irritation or inducing sensitization."
Study 02
Skin Irritation Test — OECD 439
LifeNet Health LifeSciences · Kalamazoo, MI
Conducted using three MatTek EpiDerm™ reconstructed human epidermis tissues. The report identifies the study as non-GLP and states that it was not subject to periodic quality-assurance inspections and its draft was not reviewed by LifeNet Health Quality Assurance. The report's narrative and table contain conflicting tissue-viability values; written reconciliation is required before a quantitative public claim.
Study record
- Reported Classification
- No Category (Non-Irritant); numerical reconciliation pending
- Tissue Viability
- Conflicting narrative and table / conclusion values
- Source Status
- Written reconciliation requested before launch
- Test Article
- Hirudin Topical Serum (2%); applied neat; lot/batch not provided
- Report Signatory
- Jamin A. Willoughby, Sr., Ph.D.
- Tissue Replicates
- Three reconstructed epidermis tissues
- Test Model
- MatTek EpiDerm™ reconstructed epidermis
- Standard
- OECD Test Guideline 439
- Study Number
- LNH-S-095-003
PENDING
Source Reconciliation
The report's narrative and table contain conflicting viability values. A numerical result is not presented while reconciliation is pending.
The table and conclusion classify the test article as No Category (Non-Irritant). The numerical discrepancy and the report's non-GLP and quality-assurance limitations remain part of the supplied record.
Study 03
12-Week Cosmetic Stability Study
Eurofins CRL, LLC
The supplied report describes a 12-week cosmetic stability study with a 40°C / <60% RH stress condition. The archive is missing the stated final page and complete week-12 preservative-efficacy result, so no overall stability or shelf-life conclusion is presented here.
12
Week Study
The supplied source is incomplete. It does not establish a complete final stability or shelf-life conclusion.
Stability record
| Parameter | Supplied record |
|---|---|
| Study Duration | 12 weeks; final source incomplete |
| Stress Condition | 40°C / <60% RH |
| Reported Measures | Colour, odour, texture, packaging, pH, viscosity, microbial count, preservative efficacy |
| Week-12 Preservative Result | Blank in the supplied report |
| Source Status | Complete final report requested before launch |
Safety Guidance
Before your ritual.
Read the guidance.
Read these considerations before use and always follow the product label.
Pregnancy & Breastfeeding
Consult a healthcare professional before use if pregnant or breastfeeding.
Sensitive Skin
109 of the 221 RIPT completers reported sensitive skin. No adverse events were reported during the study; individual reactions remain possible.
Fitzpatrick Representation
Fitzpatrick phototypes I-VI were represented among study participants.
External Use Only
Topical application only. Avoid eyes and mucous membranes. Keep out of reach of children.
Storage
Follow the product label. Store at room temperature and protect from direct sunlight. The supplied stability report is incomplete.
This product is cosmetic and intended for external use. Information on this page is not medical advice. If you have a medical condition or concern, consult a qualified healthcare professional before use.
The full record
Download all three
study reports.
Download the three supplied report PDFs. The archive includes the source limitations described above; the final stability report is incomplete.